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A D O'Brien Selected Research

Shiga Toxin (Shigella Toxin)

4/2015Protective efficacy and pharmacokinetics of human/mouse chimeric anti-Stx1 and anti-Stx2 antibodies in mice.
12/2014Enhanced virulence of the Escherichia coli O157:H7 spinach-associated outbreak strain in two animal models is associated with higher levels of Stx2 production after induction with ciprofloxacin.
3/2014Oral intoxication of mice with Shiga toxin type 2a (Stx2a) and protection by anti-Stx2a monoclonal antibody 11E10.

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A D O'Brien Research Topics

Disease

3Colitis
04/2015 - 03/2014
2Hemolytic-Uremic Syndrome
12/2014 - 03/2014
2Infections
10/2012 - 10/2001
1Body Weight (Weight, Body)
04/2015
1Weight Loss (Weight Reduction)
03/2014
1Anthrax
10/2012
1Diarrhea
11/2005
1Prostatitis
10/2001
1Inflammation (Inflammations)
10/2001
1Urologic Diseases (Urinary Tract Disease)
06/2001
1Urinary Tract Infections (Urinary Tract Infection)
10/2000
1Fibrosis (Cirrhosis)
09/2000
1Pulmonary Fibrosis (Fibrosing Alveolitis)
09/2000

Drug/Important Bio-Agent (IBA)

3Shiga Toxin (Shigella Toxin)IBA
04/2015 - 03/2014
2cytotoxic necrotizing factor type 1IBA
10/2001 - 10/2000
2Virulence Factors (Pathogenicity Factors)IBA
10/2001 - 06/2001
1Streptomycin (Streptomycin Sulfate)FDA Link
04/2015
1ElectrolytesIBA
03/2014
1Urea (Carbamide)FDA LinkGeneric
03/2014
1CreatinineIBA
03/2014
1NitrogenIBA
03/2014
1AntigensIBA
10/2012
1Proteins (Proteins, Gene)FDA Link
10/2012
1Anthrax Vaccines (Vaccines, Anthrax)IBA
10/2012
1VaccinesIBA
10/2012
1Shiga Toxins (Vero Toxin)IBA
11/2005
1Anti-Bacterial Agents (Antibiotics)IBA
11/2005
1Protein Synthesis InhibitorsIBA
11/2005
1Bacterial ToxinsIBA
10/2000
1GTP-Binding Proteins (G-Protein)IBA
10/2000
1Bleomycin (Blenoxane)FDA LinkGeneric
09/2000
1Immunoglobulin G (IgG)IBA
09/2000
1Messenger RNA (mRNA)IBA
09/2000
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
09/2000
1CytokinesIBA
09/2000